Peer-reviewed research evaluating the effect of the Virta Treatment demonstrates that patients can safely improve health outcomes associated with type 2 diabetes, obesity, atherogenic dyslipidemia, hypertension, and inflammation.. By impacting these chronic conditions, the Virta Treatment improves several risk factors for type 2 diabetes and cardiovascular disease 1 day ago · descriptive essay about grandparents' house, research paper about library services, essay my family for class 7, essay on diwali for std 4 diabetes 2 mellitus paper research Type, research paper job quora. Body image social media essay. Example of review essay on movie, examples of qualitative research papers essay on demand and supply BMJ Open Diabetes Research & Care is an open access journal committed to publishing high-quality basic and clinical research articles regarding type 1 and type 2 diabetes and associated complications. Submissions are subject to rigorous external peer review to
Research | Virta Health
Diabetes Action is committed to funding promising and innovative diabetes research with a special interest in integrative and nutritional therapies to prevent, treat, and cure diabetes and its complications. Researcher: Denise L. Faustman, MD, PhD. Purpose: In Augustresults of the Phase I trial showed that the pancreas of long-term diabetics was able to transiently make insulin after two doses of the Bacillus Camlette-Guerin BCG vaccine.
In a follow up report on a total of participants both treated and untreated with BCG, published in the journal Vaccinesshowed positive results in lowering blood sugars in subjects with type 1 diabetes to almost normal levels while also reducing the amount of insulin needed about one-third after 5 to 8 years from the initial treatment with the BCG vaccine without any reports of severe hypoglycemia.
The FDA approved Phase II clinical trial, which is now fully enrolled with participants with long-term type 1 diabetes, research paper about diabetes, will determine the dose and frequency of doses required to reverse type 1 diabetes. It is still necessary to obtain funding to track these patients for an additional three years with the ultimate goal of bringing BCG to market as an approved treatment for type 1 diabetes. Paper Published Research paper about diabetes Published Researcher: Angela Lombardi, research paper about diabetes, Ph.
Assistant Professor Albert Einstein Research paper about diabetes of Medicine Bronx, research paper about diabetes, NY. Currently, no curative therapy exists for T1D and the only available treatment is insulin replacement, which, though life saving, is often associated with fatal high or low glucose levels.
The aim of this research project is to treat or prevent autoimmunity in T1D by blocking antigen presentation using novel D-peptides, specifically by blocking the HLA-DQ8 peptide binding pocket from presenting diabetogenic peptides to auto reactive T-cells.
Our hypothesis is that D-peptides are specific to the cause of T1D, and should not cause general immunosuppression, reducing or eliminating the need for insulin replacement therapy, research paper about diabetes. The novel D-peptide approach can be easily expanded to patients with other autoimmune diseases carrying HLA-DQ8 or other HLA class II alleles, therefore, representing a new strategy to treat autoimmunity in general.
Researcher: Douglas Sobel, MD Professor of Pediatrics, Chief Pediatric Endocrinology Georgetown University Washington, DC, research paper about diabetes. Purpose: Islet transplantation is a promising approach to cure type 1 diabetes and some people with type 2 diabetes, but current treatment requires high dose toxic research paper about diabetes immunotherapy to prevent rejection.
Over the last year, Dr. They have synthesized a new PLGA-Microsphere system able to release three important drugs to prevent islet rejection over a very long period of time, characterized the physical properties of the microsphere system, and by doing this, have made headway to determine the optimal drug doses within the PLGA. To achieve their goal to safely inhibit rejection of islet transplantation, they will explore an important potential local immunotherapy drug entanercept, fully determine the optimal doses for the drug enladed PLGA, and assess the proper doses to prevent toxicity to the transplanted insulin producing cells in diabetic mice in order to cure them of their diabetes without rejection of the new insulin producing cells.
They hope that future studies will lead to curing people with diabetes. Researcher: Mihaela Stefan-Lifshitz, PhD Associate Professor Albert Einstein College of Medicine Bronx, NY. Purpose: The rise in the incidence of type 1 diabetes T1Despecially in industrialized countries, can only be explained by a prevailing influence of environmental factors interacting with common genetic variants that predispose to T1D. Preliminary epidemiological data support an association between chemical exposure and T1D and there is evidence that such exposures can impact Beta-cell function and contribute to the development of autoimmunity.
Despite these correlations, there are no studies directed towards understanding the role of industrial chemical exposure in T1D development. This leaves a gap in our understanding of the T1D etiology and its increasing incidence. Stefan-Lifshitz has developed a strategy which integrates complementary approaches to efficiently evaluate the association of environmental chemicals and chemical mixtures with Research paper about diabetes development and to dissect the mechanisms by which research paper about diabetes trigger T1D in susceptible individuals.
These studies will set the rationale for development of prevention strategies based on the mechanisms causing the disease. Researcher: EunSeok Cha, Ph. Purpose: Individuals with early-onset type 2 diabetes before age 40 have much greater risks of developing chronic diabetes complications compared to those with late-onset diabetes after age 40even if they have had diabetes the same length of time.
However, current screening, prevention, and treatment guidelines for early-onset are normed for those of late onset. Using data from a landmark observational study, the Coronary Artery Risk Development in Young Adults, this study aims to identify possible differences in the predictors of developing pre-diabetes and type 2 diabetes between early and late onset type 2 diabetes groups.
Contributing factors to generate different progression mechanisms in early and late-onset diabetes will be examined. Findings will provide information to increase the precision of diabetes prevention, identification, and care for individuals at risk for and with early onset type 2 diabetes. Purpose: Type 2 diabetes is a fastest-growing health problem in the US. It is a result of insulin resistance and loss of insulin secreting beta-cells.
The goal of this research is to identify low-cost, natural compounds to prevent and treat T2D. Liu discovered for the first time that hispidulin, a compound isolated from the herb Salvia plebaia, which is also abundant in oregano, acts in the gut to promote beta-cell function and ameliorates T2D, research paper about diabetes sulforaphane, research paper about diabetes, a research paper about diabetes molecule derived from cruciferous vegetables, research paper about diabetes, is a potent insulin sensitizer in research paper about diabetes body of T2D mice.
In this project Dr. Liu will investigate whether a combination treatment with hispidulin and sulforaphane is more effective in preventing T2D development by simultaneously improving insulin sensitivity and preserving functional beta-cell mass in T2D mice. The results from this grant could lead to developing strategy for using these natural products as an alternative or complementary therapy for T2D.
Researcher: Andrew C. Shin, Ph. Research paper about diabetes Professor Director, Mouse Metabolic Phenotyping Facility Texas Tech University Lubbock, Texas. Purpose: Branched-chain amino acids BCAAs are essential amino acids we cannot make in our body, thus we need to obtain through diet.
Recent studies show that circulating BCAAs are elevated in obese and diabetic individuals, and that BCAA supplementation through diet can lead to insulin resistance and abnormally high glucose levels.
These findings indicate that BCAAs may have a causal role in the development of obesity and diabetes, but how and why they are elevated to begin with has been a big black box.
Shin has discovered earlier that insulin action in research paper about diabetes brain region called the mediobasal hypothalamus MBH controls circulating BCAAs. The present study proposes to identify and test the role of specific neuronal populations within the MBH for BCAA regulation. Research paper about diabetes Guoxun Chen, research paper about diabetes, Ph. Associate Professor, Dept. of Nutrition The University of Tennessee, Knoxville Knoxville, TN, research paper about diabetes.
Purpose: The numbers of patients with type 2 diabetes T2D in the U. is rising. It is urgent to find alternative, complementary, and nutritional therapies for the prevention and treatment of T2D, research paper about diabetes. Oxidative stress contributes to abnormalities of T2D. Therefore, antioxidants have been implied to have anti-diabetic functions.
Clinical trials using high doses of Vitamin C or E individually have shown some promising results in T2D patients. However, whether a continuous dietary presence of vitamin C our E, or their combination is critical for their anti-diabetic effects remains unanswered.
This nutrition research proposal is to investigate the effects of a combination of high doses of dietary vitamins C and E on the development of type 2 diabetes in Zucker diabetic rats, a well known T2D model. The results will lead us to use commonly available antioxidants, vitamins C and E, as nutritional therapies to prevent and treat diabetes and its complications. Researcher: Meredith Hawkins, MD Professor, Dept. of Medicine Endocrinology Albert Einstein College of Medicine Bronx, NY.
Purpose: Patients with type 2 diabetes have inappropriately high blood sugar levels, which is predominately produced by the liver. There is evidence in humans and rats that the brain normally regulates sugar production by the liver.
However, this regulation is lost in people with type 2 diabetes. These studies are likely to provide novel therapeutic target for controlling blood sugar levels in type research paper about diabetes diabetes.
Researcher: Robert P. Purpose: Cardiovascular disease is the major cause of death in patients with type 1 diabetes. Increased inflammation causes future atherosclerosis and cardiovascular disease. Inflammation increases with increased glucose following a meal. Adolescents with type 1 diabetes have increased inflammation. The glycemic index quantifies the expected rise in glucose for a specific food 2 hours after a meal with a smaller increase for low glycemic index foods.
The effects of low glycemic index meals on inflammation following a meal have not been studied in adolescents with type 1 diabetes. Inflammation before and after low and high glycemic index meals will be studied in 20 adolescents with type 1 diabetes.
Changes in vascular and renal function will also be measured. If improvements in inflammation, vascular and renal function are found, this would strongly indicate that low glycemic index diets have the potential to reduce complications in type 1 diabetes.
Researcher: Kevin W. Huggins, Ph. Associate Professor Research paper about diabetes University Auburn, AL. Purpose: Type 2 diabetes is associated with neurodegeneration leading to cognitive deficits. The mechanism s underlying this diabetes-associated cognitive decline is poorly understood but may be related to an increase in diabetes-induced inflammation in the brain.
Increased consumption of omega-3 polyunsaturated fatty acids PUFA from cold water fish and fish oils have been associated with a decreased risk of diabetes and cognitive decline associated with diabetes. This effect may be related to the anti-inflammatory properties of omega-3 PUFA. Specifically, increased brain omega-3 PUFA increases the production of pro-resolving lipid mediators which decrease inflammation.
The goal of this study is to determine the role of omega-3 derived pro-resolving lipid mediators on inflammation in the brain of diabetic mice. Researcher: Laurie P. Shornick, PhD Associate Professor of Biology Saint Louis University St. Louis, MO. Purpose: Diabetic patients often develop non-healing foot ulcers that result in lower limb amputations.
Honey has been used for centuries as a complementary treatment for wound healing; however, it is sticky and difficult to apply. When honey warms to body temperature, it may also leak out of the wound. Shornick proposes an innovative three-dimensional wound dressing containing New Zealand manuka honey which has special properties.
The dressing will provide a structure for cells to migrate into the wound, research paper about diabetes, and the honey will provide anti-bacterial protection and will promote the formation of new tissue and blood vessels. Because pigs have skin very similar to human skin, a diabetic pig model will be used research paper about diabetes test the efficacy of the honey-embedded wound dressings. Researcher: Bin Xu, research paper about diabetes, Ph. Research paper about diabetes Professor Principal Investigator Biomanufacturing Research Institute and Technology Enterprise BRITE North Carolina Central University Durham, NC.
Purpose: The goal of this project is to investigate the novel functions of botanical compound research paper about diabetes acid RA and its analog RA-amide, in the prevention and treatment of diabetes and its complications. Due to a rapidly aging population and the modern sedentary lifestyle, type 2 diabetes T2D and related neurodegeneration are reaching epidemic proportions.
Currently, there is no known cure for these diseases.
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Peer-reviewed research evaluating the effect of the Virta Treatment demonstrates that patients can safely improve health outcomes associated with type 2 diabetes, obesity, atherogenic dyslipidemia, hypertension, and inflammation.. By impacting these chronic conditions, the Virta Treatment improves several risk factors for type 2 diabetes and cardiovascular disease Cytomegalovirus - A research paper on Cytomegalovirus examine the virus that has various symptoms and infections that impacts men, women, and children equally. Diabetes - Research papers on diabetes look at many factors in the onset of the disease, including biology, stress, diet and culture Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination Read more
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